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Hematopoiesis is a process of continuous replacement of most mature blood cells. New produced blood cells must be adequate to meet the basic demand of body. Hematopoiesis process needs an ample supply of minerals (e.g., iron, copper, and cobalt) and vitamins (e.g., vitamin B12, folic acid, ascorbic acid, pyridoxine, and riboflavin). Normal hematopoiesis process produces more than 400 billion blood cells each day, this production can be increased several-fold with increased demand by hematopoietic agents.

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