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A patient diagnosed with early lung cancer delaying the surgery poses serious health risk leading to the spread and upstaging of the tumor. The American Association for Thoracic Surgery concluded that there was a 4% increased risk of upstaging of patients with stage 1 non-small cell lung cancer to stage 2, 3, or 4, each week before their surgery. The National Comprehensive Cancer Network suggests lung cancer resection surgery should be done within eight weeks for stage 1 NSCLC.
The surge in mortality rates of patients with lung cancer can be traced as early as 1930s.

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