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Did you know there’s a gland deep down in your brain in charge of how your body responds to various stimuli and situations? Yes, there are actually several glands in your brain, and one of the most important among them is called the hypothalamus. 

The human brain is also home to two other important glands – the pineal, and the pituitary gland. But why exactly is the hypothalamus so important, and what happens if it gets damaged or fails to perform its functions effectively? Are there warning signs of damage?

Let’s find out below! 

What Is the Hypothalamus? 

By simple definition, the hypothalamus is a small gland located in the human brain that serves as a central point of the endocrine (hormonal) system. You can look at it as the chief of all other endocrine glands in the body because it coordinates their functions.

As a result, this gland regulates numerous complex functions that are critical to the body’s proper functioning. It also serves as a link between the nervous system and the endocrine system.

It also secretes several hormones and sends them to the pituitary gland, which in turn disseminates them to various areas of the body where they are needed.

Anatomy and Functions of The Hypothalamus 

So where exactly is the hypothalamus located, and what does it look like?

The hypothalamus sits right above the pituitary gland and below the thalamus in the brain’s cerebrum. It takes the structure of a small cone with a tube connecting to the pituitary gland that sits right below it.

Functions Of the Hypothalamus 

As earlier iterated, the hypothalamus plays numerous roles in the body. For instance, it plays a critical role in thermoregulation, making it an important part of the body’s “heating and cooling system.”

It is also involved in homeostasis, a biological process in which the body achieves and maintains a stable, balanced state, especially when it comes to important elements like energy, sugars, salts, and water.

Another vital role played by the hypothalamus is its involvement in the regulation of emotional behavior, which affects things like mood, cognition, memory, appetite, and even sleep.

Perhaps the most important function of all is its involvement in modulating the endocrine system via the tubular link with the pituitary gland!

Common Health Issues Related to Hypothalamus Dysfunction 

When the hypothalamus suffers damage, either from birth or at some point in a person’s life, a diverse range of health issues could possibly develop. Some of these may include:

  • Insomnia: The hypothalamus plays a critical role in sleep regulation.
  • Hypothalamic Obesity: Since it regulates appetite and energy expenditure, an injured hypothalamus can sometimes result in eating disorders, which may cause obesity.
  • Diabetes Insipidus: Where too much water is lost through urine because the hypothalamus doesn’t release vasopressin or Antidiuretic hormone (ADH), a hormone that helps water reabsorption in the kidneys or the renal system.
  • Body Temperature Fluctuations: A dysfunctional hypothalamus could also make you shiver when it’s hot or sweat when it’s chilly-cold.

Besides these, hypothalamus damage may also cause a consequential condition known as hypopituitarism, which stems from the insufficient production of hormones by the pituitary gland.

This is because the hypothalamus generates several hormones that affect the function of the pituitary gland, and could lead to problems like prolactin deficiency, hypogonadism, hypothyroidism, adrenal insufficiency, and even growth hormone deficiency, just to name a few.

Some infertility and erection problems can also be traced back to hypothalamus damage, which is sometimes known to cause sex gland deficiency.

Common Causes of Hypothalamus Damage 

Hypothalamus dysfunction or damage may stem from a wide range of causes. If not acquired at birth, some of the most common causes of hypothalamus damage include:

Brain Surgery 

Remember, the hypothalamus is part of the cerebrum’s limbic system, making it extremely delicate. If a brain surgery to this area is improperly conducted errors could occur, leading to damage to this small yet highly important gland.

This is all the more reason to seek highly recognized professionals with various surgery specialties when it comes to brain surgery, especially those that involve brain disorders, head injuries, tumors, and malformations.

Apart from medical errors or side effects of surgery, other common causes include the following:

  • Aneurysm:
  • Brain hemorrhage:
  • TB
  • Brain disorders like Kallmann and Prader-Willi syndrome
  • Eating disorders

Ways To Tell the Hypothalamus Is Damaged 

Even though a doctor’s appointment is the best way to be sure, several signs and symptoms could suggest a damaged hypothalamus. Some of these may include:

  • Unexplained fatigue or weakness
  • Unexplained headaches
  • Vision loss
  • Unusual fluctuations in blood pressure or body temperature
  • Sudden weight loss or gain
  • Mood and appetite changes
  • Sleep problems
  • Infertility
  • Frequent urination
  • Frequent thirst or dehydration

Treatment for Hypothalamus Damage 

How hypothalamic dysfunction or damage is treated may vary from one case to the other. More often than not, it is a multi-procedural approach that may involve medications that treat hormonal imbalance or replace deficient hormones, as well as those that help regulate appetite.

If there are tumors involved, surgery or radiation could be a helpful option. All these often require the patient to eat a properly-balanced diet, get proper sleep, and engage in regular exercise to boost overall health as soon as the doctor permits it.

Hypothalamus damage may not be as common as the regular cold, but it does affect a significant number of people around the world.

The cone-shaped gland sitting in your brain’s cerebrum serves numerous crucial functions in the body, so you have more than enough reason to watch out for any signs that it could be damaged and take action as soon as possible.